Melatonin, a hormone produced by the pineal gland in the brain, is best known for its role in regulating sleep-wake cycles. However, research has also suggested that melatonin has various anti-cancer properties. Some studies suggest that melatonin may have potential as an adjunctive therapy to enhance the efficacy of cancer treatments and reduce their side effects. Its anticancer effect is thought to be due to its antioxidant activity, modulation of cancer-related genes, interference with cancer cell signalling, and immune response regulation.
- Melatonin, a Full Service Anti-Cancer Agent: Inhibition of Initiation, Progression and Metastasis - PMC
- Melatonin in Cancer Treatment: Current Knowledge and Future Opportunities - PMC
